The Foundation

AriSLA, the Italian Research Foundation for Amyotrophic Lateral Sclerosis (ALS) is one of the leading non-profit organizations in Italy and Europe, whose institutional purpose is to to support excellent scientific research in Italy with the aim of defeating this very serious disease, whose causes are still unknown and for which there is currently no cure. To reach this goal, the Foundation is working together with the Italian scientific community, playing the role of catalyst and driving force, and providing economical, scientific and technical support.

AriSLA was founded in December 2008 by AISLA Onlus(the main ALS Italian patient organisation), Fondazione Cariplo, Fondazione Telethon, and Fondazione Vialli e Mauro per la Ricerca e lo Sport Onlus.

We are committed to coordinating and promoting research projects, funded and selected through an evaluation process based on the most consolidated and transparent peer-review criteria. Since its start, AriSLA adopted a rigorous peer review system to select the best research projects mainly through a bottom-up approach. In these years,  11 Calls for research proposals have been issued concerning both full grants, projects with a solid background and consistent preliminary data, and pilot grants, 1-year projects with highly innovative and original hypotheses, where preliminary data are either not available or to be consolidated.

We support research in different but complementary areas: Basic, Translational, Clinical and Technological Research. The main research lines comprise studies aimed the identify the genetic causes of ALS; studies of the mechanism underlying the onset of the disease; projects that search for new biomarkers for prognosis and early diagnosis or for new preclinical therapeutic approaches on in vitro and in vivo models of the disease We also sustain clinical trials to test of new pharmacological treatments and projects aimed to design tools to support everyday life and high-tech electronic aids for communication and motor skills.

Since 2008, over 11.5 million euros have been invested in research activities, funding  120 research groups and over 250 researchers throughout Italy.

72 Research Projects have been funded:

  • 47 projects of Basic Research;
  • 14 projects of Translational Research;
  • 4 projects of Technological Research;
  • 7 projects of Clinical Research.

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