the new research winner projects of the 2018 arisla call


AriSLA - the Italian Research Foundation for ALS - announced the four new research projects funded through its eleventh "Call for Research Projects".  The total investment will be of € 848.980: the Foundations dedicated to scientific research on ALS more than 12,2 mln euro since 2009, supporting 72 projects and more than 260 researchers in Italy.

As for all the Call for Projects launched by the Foundation, the 2018 winner projects have been selected through a careful peer-review evaluation process made by AriSLA International Scientific Committee: peer-review is an accredited method among the international scientific community and based on the principles of transparency, scientific merit and impartiality in the proposals selection.

CALL CHARACTERISTICS: Researchers from Italian Universities and public and private non-profit research Institutes could participate in the 'Call for Research Projects' 2017. The Application could be presented in partnership with foreign companies and research organizations.

 researchers with a solid curriculum, but also to young scientists with at least three years' experience in the laboratory.

AREAS OF FUNDING: The Call was opened to Full Grants, i.e. projects developing promising areas of study based on a solid background, coherent preliminary data which propose multidisciplinary and highly translational approaches. The invitation was to present proposals in the field of Basic and Translational Research with a maximum duration of 36 months and a maximum requested budget of 240,000 euros.

AriSLA received, through its online platform 83 proposals, confirming that the AriSLA Call represents an important opportunity for the Italian scientific community that deals with ALS.



Nr Title PI Value (euro) Type of research Duration (months) PDF
1 'MLOpathy' Membrane-less organelle pathology in ALS: identification of causes and rescuing factors Serena Carra, Department of Biomedical, Metabolic Sciences and Neuroscience, Università degli Studi di Modena e Reggio Emilia Partner: Angelo Poletti, Department of Pharmacological and Biomolecular Sciences (DiSFeB),Università degli Studi di MilanoOrietta Pansarasa, Centre of Genomics and Post-genomics, Fondazione Mondino Istituto Neurologico Nazionale IRCCS, Pavia 240.000 Traslational 36 icona_pdf
2 'Target-RAN'  Targeting RAN translation in ALS Alessandro Provenzani, CIBIO – Università degli Studi di Trento Partner: Angelo Poletti, Department of Pharmacological and Biomolecular Sciences (DiSFeB), Università degli Studi di Milano 240.000 Basic 36 icona_pdf
3 'PathensTDP' Defining the role of hnRNP proteins in enhancing TDP-43 pathology Emanuele Buratti, International Centre for Genetic Engineering and Biotechnology – ICGEB, TriestePartner: Patrizia Longone, Fondazione Santa Lucia IRCCS, Roma 208.980  Basic 36 icona_pdf
4 'SPLICEALS' Dissecting the functional interaction between FUS and hnRNP A2/B1 in the pathogenesis of ALS Mauro Cozzolino, Institute of Translational Pharmacology, National Research Council, RomaPartner: Nadia D'Ambrosi, Department of Biology, Università di Roma Tor Vergata Gianluca Cestra, Institute of Biology and Molecular Pathology, CNR, RomaThe project is also carried out in collaboration with the Neurobiochemistry Laboratory at Fondazione Santa Lucia IRCCS. 160.000 Basic 24 icona_pdf